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Damien, Great post, I find these findings so interesting and so important. Have you looked at difference in sero-discordance according to either the average age of the couple or relative to how long the couple has been in a stable relationship? We know that women tend to get infected at a younger age than men, so we might see higher rates of female sero-discordance in newer couples rather than older couples. This might hint at a possible mechanism. But of course if you don't, than that really challenges the self reported data of sexual activity outside of marriage. Karen Grepin http://www.karengrepin.com/